The 49ers acquired McCaffrey Thursday night in a trade with the Carolina Panthers for second-, third- and fourth-round picks in 2023, and a fifth-rounder in 2024.
The 49ers had a brief practice on Saturday, after which coach Kyle Shanahan
determined that McCaffrey had a strong enough knowledge of the play book to suit up and see action.
McCaffrey, 26, flew to the Bay Area on Friday morning and watched most of practice that day while he began learning the 49ers' game plan for facing the Chiefs on Sunday.
Against Kansas City, McCaffrey is physically capable of handling a heavy workload.
The question now is how much of the offense he can learn before the game.